Endothelin-1 in cardiovascular physiology
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چکیده
منابع مشابه
Physiology and pathology of endothelin-1 in renal mesangium.
Mesangial cells (MCs) play a central role in the physiology and pathophysiology of endothelin-1 (ET-1) in the kidney. MCs release ET-1 in response to a variety of factors, many of which are elevated in glomerular injury. MCs also express ET receptors, activation of which leads to a complex signaling cascade with resultant stimulation of MC hypertrophy, proliferation, contraction, and extracellu...
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Introduction: The cases of misconceptions are intellectual models of phenomena that are different from accepted scientific models of the same phenomena. The purpose of this study was to investigate the prevalence of cardiovascular misconceptions among students, and evaluate the role of cardiovascular physiology courses in eliminating them. Methods: This descriptive study was performed on 348 u...
متن کاملTranslational physiology TRANSLATIONAL PHYSIOLOGY Endothelin-1 decreases CD36 protein expression in vascular smooth muscle cells
Kwok CF, Juan CC, Ho LT. Endothelin-1 decreases CD36 protein expression in vascular smooth muscle cells. Am J Physiol Endocrinol Metab 292: E648–E652, 2007. First published September 19, 2006; doi:10.1152/ajpendo.00084.2006.—Recent studies have shown that CD36 plays important roles as a major scavenger receptor for oxidized low-density lipoproteins and as a crucial transporter for long-chain fa...
متن کاملUpregulation of Endothelin-1/Endothelin A Receptor Expression Correlates with Heparanase Expression in Ovarian Carcinoma
Background: Heparanase and endothelin-1/endothelin A receptor (ET-1/ETAR) expressions increase in cancer. This condition enhances tumor progression and correlates with poor survival. Limited data are documented regarding the role of heparanase and ET-1/ETAR in epithelial ovarian cancer (EOC). We sought to characterize the correlation between heparanase and ET-1/ETAR in EOC.Methods: Thirty patie...
متن کامل[Endothelin-1 production and its involvement in cardiovascular diseases].
Endothelin (ET) has been implicated in the pathogenesis of several cardiovascular disorders because of its powerful vasoconstrictor and growth-promoting properties. The ET family consists of three isoforms, ET-1, ET-2 and ET-3. ET-1 appears to be the predominant member of the family generated by vascular endothelial cells. In view of the multiple cardiovascular actions of ET-1, there has been m...
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ژورنال
عنوان ژورنال: Clinical Hemorheology and Microcirculation
سال: 1996
ISSN: 1386-0291
DOI: 10.3233/ch-1996-16513